Characterization of a bacteriocin-like substance produced by a vaginal Lactobacillus salivarius strain.

نویسندگان

  • V S Ocaña
  • A A Pesce De Ruiz Holgado
  • M E Nader-Macías
چکیده

A novel bacteriocin-like substance produced by vaginal Lactobacillus salivarius subsp. salivarius CRL 1328 with activity against Enterococcus faecalis, Enterococcus faecium, and Neisseria gonorrhoeae was characterized. The highest level of production of this heat-resistant peptide or protein occurred during the late exponential phase. Its mode of action was shown to be bactericidal. L. salivarius subsp. salivarius CRL 1328 could be used for the design of a probiotic to prevent urogenital infections.

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عنوان ژورنال:
  • Applied and environmental microbiology

دوره 65 12  شماره 

صفحات  -

تاریخ انتشار 1999